Gene drive reversibility introduces new layer of biosafety

In parallel with their development of the first synthetic gene drives - which greatly increase the chance a specific gene will be passed on to all offspring - George Church, Ph.D., and Kevin Esvelt, Ph.D., helped pioneer ...

Dually noted: New CRISPR-Cas9 strategy edits genes two ways

The CRISPR-Cas9 system has been in the limelight mainly as a revolutionary genome engineering tool used to modify specific gene sequences within the vast sea of an organism's DNA. Cas9, a naturally occurring protein in the ...

Batting practice in the genome

In the biochemical game of genetics, it was thought that the proteins controlling gene regulation in animals were either spectators or players.

Clamshell-shaped protein puts the 'jump' in 'jumping genes'

Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes. The clamshell shape, they say, has ...

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