Control of gene expression: Histone occupancy in your genome

When stretched out, the genome of a single human cell can reach six feet. To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating units—each unit known ...

Tiny roundworm points to big promise

Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic ...

Cellular network transforms fungus when temperatures rise

(Phys.org) —When the infectious fungus Histoplasma capsulatum feels the temperature start to rise, it undergoes a transformation. As it shifts its shape from long filaments to oval cells, the pathogen switches on genes ...

Gene network illuminates stress, mutation and adaptation responses

For much of her professional life, Dr. Susan Rosenberg has studied the puzzling response of bacteria to stress and the mutations that result. In the current issue of the journal Science, she puts together the pieces of that ...

page 19 from 40