Lysosomal protein driver of neurodegenerative diseases revealed

Lysosomes, tiny compartments within cells known as the garbage disposals for molecules that need to be degraded, are critical to cell function and a person's health; disruption of lysosomal protein function is linked to a ...

HPV discovery yields breakthrough in understanding protein activity

A new study led by Yale scientists shows that the activity of a portion of a human papillomavirus (HPV) protein does not depend on its amino acid sequence or composition. This discovery challenges the widely held belief that ...

Researchers reveal universal mechanisms of DNA and RNA deformations

DNA and RNA, the two main types of nucleic acid and the building blocks of life, are susceptible to environmental stimuli, which can cause them to deform, bend or twist. These deformations can significantly affect gene regulation ...

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