UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.
Biochemistry
Jun 1, 2017
0
7
Subgroups of tuberculosis (TB)-causing bacteria can persist even when antibiotics wipe out most of the overall population. The need to eliminate these persistent subpopulations is one reason why TB treatment regimens are ...
Cell & Microbiology
May 31, 2017
0
109
Researchers at Karolinska Institutet in Sweden have managed to synthesise lung surfactant, a drug used in the care of preterm babies, by mimicking the production of spider silk. Animal studies reveal it to be just as effective ...
Biochemistry
May 23, 2017
0
17
Drugs manufactured by living cells, also called biologics, are one of the fastest-growing segments of the pharmaceutical industry. These drugs, often antibodies or other proteins, are being used to treat cancer, arthritis, ...
Nanophysics
May 22, 2017
0
12
Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing ...
Analytical Chemistry
May 16, 2017
0
4
Resistance to malaria drugs means that pregnant women are unable to overcome the anaemia caused by the malaria parasite – and their babies are born undersized. A study carried out at Karolinska Institutet, however, exposes ...
Cell & Microbiology
May 9, 2017
0
35
Bacterial populations pose an intriguing puzzle: in so-called isogenic populations, all bacteria have the same genes, but they still behave differently, for example grow at different speeds. Researchers at the Institute of ...
Cell & Microbiology
Apr 20, 2017
0
6
An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science ...
Cell & Microbiology
Apr 11, 2017
0
72
Potential drugs that seem promising in the lab, but don't show any activity in a person: they cost the industry an incredible amount of time and money. That's why Indira Nederpelt focuses on a more efficient search for new ...
Biochemistry
Apr 5, 2017
0
5
EPFL scientists have created a new computer model that can help better design of allosteric drugs, which control proteins "at a distance".
General Physics
Feb 20, 2017
0
745
