Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally.
Materials Science
Jul 27, 2022
0
87
A study published in Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids. ...
Biochemistry
Jul 22, 2022
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18
A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.
Biochemistry
Jul 14, 2022
0
18
Mass-spectrometry based proteomics is the big-data science of proteins that allows the monitoring of the abundance of thousands of proteins in a sample at once. Therefore, it is a particularly well-suited readout for discovering ...
Biochemistry
Jun 29, 2022
0
32
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Led by Jun Wang, Associate Professor of Biomedical Engineering ...
Biotechnology
Jun 29, 2022
0
32
Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their ...
Biochemistry
Jun 23, 2022
0
61
Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, Ph.D., of the Stony Brook Cancer Center and Renaissance School ...
Biochemistry
Jun 21, 2022
0
77
A collaborative effort has revealed a new type of triterpene, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type ...
Biochemistry
Jun 1, 2022
0
140
Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
0
5
