An increasing number of bacteria have become resistant to many commonly used antibiotics. Researchers from Bochum have discovered a fresh opportunity for a potential active molecule whose predecessor was rejected. By studying ...
Biochemistry
May 16, 2024
0
1
AlphaFold 3, unveiled to the world on May 9, is the latest version of an algorithm designed to predict the structures of proteins—vital molecules used by all life—from the "instruction code" in their building blocks.
Biotechnology
May 13, 2024
0
3
Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes that grant them their function.
Bio & Medicine
May 10, 2024
0
216
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open ...
Biochemistry
May 6, 2024
0
27
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
Biochemistry
Apr 25, 2024
0
54
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature ...
Biochemistry
Apr 24, 2024
1
37
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
0
46
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
0
35
Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers at Brown University has developed a way of using machine learning ...
Biotechnology
Mar 27, 2024
1
67
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins—a new but largely unrealized approach to the treatment ...
Cell & Microbiology
Mar 22, 2024
0
30
