Using DESY's ultra bright X-ray source PETRA III, scientists have resolved the molecular structure of two promising drug candidates from the new group of Spiegelmers for the first time. The results provide a deeper understanding ...
Biochemistry
Apr 22, 2015
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17
Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA intermediaries between ...
Cell & Microbiology
Apr 6, 2015
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27
An international team of researchers has shed light on the molecular mechanism behind the importance of water for functional protein dynamics. The scientists have discovered that water's ability to flow on the surface of ...
Biochemistry
Mar 17, 2015
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53
Every cell is encapsulated and protected by a thin membrane made of greasy molecules called lipids. Assemblies of equally greasy protein molecules span the membrane, forming passageways that control the flow of signaling ...
Cell & Microbiology
Jan 7, 2015
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16
A major challenge faced by the pharmaceutical industry has been how to rationally design and select protein molecules to create effective biologic drug therapies while reducing unintended side effects - a challenge that has ...
Biochemistry
Nov 18, 2014
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0
Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery—it is extremely ...
Biotechnology
Nov 17, 2014
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0
Green tea has long been known for its anti-oxidant, anti-cancer, anti-aging and anti-microbial properties. A group of researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR has taken the health ...
Bio & Medicine
Oct 6, 2014
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1
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
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1
Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...
Biochemistry
Aug 20, 2014
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0
Researchers from Carnegie Mellon University have developed a novel method for creating self-assembled protein/polymer nanostructures that are reminiscent of fibers found in living cells. The work offers a promising new way ...
Materials Science
Jul 31, 2014
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