Mechanism of actions of cholecystokinin receptors revealed

Cholecystokinin (CCK) and gastrin are the earliest discovered gastrointestinal hormones. They are the most abundant peptides in gastrointestinal tract and central nervous system, acting as physiologically important hormones ...

How promiscuous protein droplets regulate immune genes

Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its orientation and local environment. New research demonstrates that the glucocorticoid receptor ...

Toward one drug to treat all coronaviruses

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against ...

Harnessing AI to discover new drugs inspired by nature

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect ...

COVID gets quantum treatment for drug discovery

Since the first known case of COVID-19 in December 2019, the disease has infected over 180 million people and killed nearly four million. A successful group of vaccines that target the coronavirus's spike protein has started ...

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