The potential of modular design for brand new proteins that do not exist in the natural world is explored Dec. 16 in the journal Nature. The reports are the latest in a recent series of developments toward custom-designing ...
Cell & Microbiology
Dec 16, 2015
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8
Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task ...
Biochemistry
Oct 23, 2015
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920
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...
General Physics
May 7, 2015
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56
Every cell is encapsulated and protected by a thin membrane made of greasy molecules called lipids. Assemblies of equally greasy protein molecules span the membrane, forming passageways that control the flow of signaling ...
Cell & Microbiology
Jan 7, 2015
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16
(Phys.org) —Researchers have tried for decades to understand the undulations and gyrations that allow transport proteins to shuttle molecules from one side of a cell membrane to the other. Now scientists report that they ...
Biochemistry
Dec 2, 2013
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0
Computer-designed proteins that can recognize and interact with small biological molecules are now a reality. Scientists have succeeded in creating a protein molecule that can be programmed to unite with three different steroids.
Biotechnology
Sep 5, 2013
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0
A research team from the National Physical Laboratory (NPL), the University of Edinburgh and IBM's TJ Watson Research Center has revealed a major breakthrough in the modelling of water that could shed light on its mysterious ...
Condensed Matter
Jun 4, 2013
3
2
Structure analysis of the trypanosomal protein Cathepsin B is among the scientific breakthroughs of 2012.
Biochemistry
Dec 21, 2012
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0
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer.
Cell & Microbiology
Dec 10, 2012
1
0
(Phys.org)—By following certain rules, scientists can prepare architectural plans for building ideal protein molecules not found in the real world. Based on these computer renditions, previously non-existent proteins can ...
Biochemistry
Nov 29, 2012
0
0
