A new way of fighting bacteria?

In bacteria, toxin-antitoxin systems consist of a set of two closely linked genes. Situated on the same chromosome, they encode both a protein 'poison' and a counteracting 'antidote'. Under normal conditions, the antitoxin ...

A step closer to understanding fertilization

Researchers at Karolinska Institutet in Sweden have taken a step closer to understanding the mechanism that leads to the fusion of egg and sperm at fertilisation. Using the technique X-ray crystallography, they have determined ...

New research suggests a novel route in the fight against cancer

In a new study published today in Nature Structural and Molecular Biology, scientists from the University of Surrey have uncovered a collection of important proteins that carry out and regulate critical biological processes. ...

RNA's part in determining the health of stem cells

What makes stem cells so interesting is that they are pluripotent: they have the potential to become any cell in an organism. Their ability to differentiate into any cell and be used to replace those that are damaged or ...

DNA division can slow to a halt

A key mystery of the DNA replication process has been unraveled by researchers from King Abdullah University of Science and Technology (KAUST).

Faster, not stronger: How a protein regulates gene expression

Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by ...

Epigenetic 'switch' regulates RNA-protein interactions

Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...

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