Fifteen years ago, a class of proteins was discovered, which give humans innate immunity to HIV-1. Unfortunately, HIV-1 is a smart virus and has evolved to battle these proteins. Northeastern researchers, with help from their ...
Biochemistry
Oct 12, 2017
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8
The catalytic activity of an enzyme called Set1A—a protein that is essential to the viability of embryonic stem cells (ESCs)—is not required for ESC self-renewal, according to a Northwestern Medicine study published in ...
Biotechnology
Oct 2, 2017
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3
Research groups from the University of Groningen have revealed a novel mechanism of ribosome dimerization in the bacterium Lactococcus lactis using cryo-electron microscopy. As this dimerization renders ribosomes more resistant ...
Cell & Microbiology
Sep 28, 2017
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4
New research provides mechanistic insight into how protein dynamics control the activity of a group of enzymes called serine proteases. As serine proteases play pivotal roles in blood coagulation, the innate immune system ...
Cell & Microbiology
Jun 27, 2017
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2
DNA contains the instructions for life, encoded within genes. Within all cells, DNA is organised into very long lengths known as chromosomes. In animal and plant cells these are double-ended, like pieces of string or shoelaces, ...
Biotechnology
Mar 23, 2017
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9
Proteins are the workhorse molecules of life. Among their many jobs, they carry oxygen, build tissue, copy DNA for the next generation, and coordinate events within and between cells. Now scientists at the University of North ...
Cell & Microbiology
Jan 5, 2017
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614
A tool that uses light to manipulate matter inside living cells has begun to explain how proteins assemble into different liquid and gel-like solid states, a key to understanding many critical cellular operations.
Cell & Microbiology
Dec 29, 2016
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436
In the lab, doctors can attach chemotherapy to nanoparticles that target tumors, and can use nanoparticles to enhance imaging with MRI, PET and CT scans. Unfortunately, nanoparticles look a lot like pathogens - introducing ...
Bio & Medicine
Dec 19, 2016
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215
A new technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has ...
Biochemistry
Dec 13, 2016
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395
The macromolecular crystallography beamlines at the BESSY II X-ray source are specially designed to highly automated structural analyses of protein crystals. With up to now more than 2,000 solved structures of protein molecules, ...
Biochemistry
Oct 4, 2016
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