"When they are healthy, they look like tiny spheres; when they are malignant, they appear as cubes" stated Giuseppe Legname, principal investigator of the Prion Biology Laboratory at the Scuola Internazionale Superiore di ...
Biochemistry
Jan 24, 2014
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Separating target molecules in biological samples is a critical part of diagnosing and detecting diseases. Usually the target and probe molecules are mixed and then separated in batch processes that require multiple pipetting, ...
Biochemistry
Sep 17, 2013
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New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...
Biochemistry
Jul 2, 2013
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(Phys.org) -- Prions, infectious agents composed of proteins with a specific misfolded and transmissible 3D structure that cuases diseases like BSE, can be present in fungal populations on a large scale, preventing the spread ...
Cell & Microbiology
Jun 19, 2012
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(Phys.org) -- University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in the pathogenesis, ...
Biochemistry
Apr 6, 2012
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The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy (BSE).
Biochemistry
Mar 21, 2011
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Special proteins known as prions, which are perhaps best known as the agents of mad cow and other neurodegenerative diseases, can also serve as an important source of beneficial variation in nature, confirms a new study in ...
Cell & Microbiology
Apr 2, 2009
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For over twenty years, scientists have known that a normal protein in the brain, PrP, or prion protein, can turn harmful and cause deadly illnesses like Creutzfeldt-Jakob disease (CJD) in humans, and bovine spongiform encephalopathy ...
Cell & Microbiology
Mar 10, 2009
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(PhysOrg.com) -- Antibodies that stick to a brain prion protein called PrP could be the key to treating prion diseases like variant CJD and preventing people accidentally exposed to prions from going on to develop the fatal ...
Feb 12, 2009
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