One step closer to artificial rhino eggs

To prevent the extinction of the northern white rhino, the international consortium BioRescue is attempting to create artificial egg cells from stem cells. A team led by MDC's Sebastian Diecke and Micha Drukker of Leiden ...

Rewiring blood cells to give rise to precursors of sperm

Different cell types—say, heart, liver, blood, and sperm cells—possess characteristics that help them carry out their unique jobs in the body. In general, those characteristics are hard-wired. Without intervention, a ...

Patterns in primordial germ cell migration

Whenever an organism develops and forms organs, a tumor creates metastases or the immune system becomes active in inflammation, cells migrate within the body. As they do, they interact with surrounding tissues which influence ...

Preventing a genetic uprising in early life

Molecules called endosiRNAs help us avoid genetic chaos, according to a new study from a team at the Babraham Institute. Much of the human genome contains pieces of DNA called transposons, a form of genetic parasite. When ...

How close are we to successfully editing genes in human embryos?

An important international summit on human gene editing recently recommended that researchers go ahead with gene editing human embryos, but keep revisiting how and when such modifications would be appropriate in the clinic. ...

Male-biased protein expression discovered in fruit flies

Fruit flies (Drosophila) are important model organisms for biological research. Molecular tools exist that can turn on (or induce) gene expression in fruit flies, allowing researchers to learn more about the functions of ...

Gene repression can be sex-specific

Researchers have shown for the first time that embryonic cells destined to become either egg or sperm rely on different methods of repressive gene regulation.

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