Stem cells made from the skin of adult, infertile men yield primordial germ cells—cells that normally become sperm—when transplanted into the reproductive system of mice, according to researchers at the Stanford University ...
Cell & Microbiology
May 1, 2014
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Researchers at the Babraham Institute have investigated the early stages of the development of cells called primordial germ cells and developed strategies to generate 'lookalike' cells in the lab. The generation of human ...
Cell & Microbiology
Oct 11, 2016
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Germline stem and progenitor cells (GSPCs), including primordial germ cells (PGCs) and germline stem cells (GSCs), generate various states of germ stem cells and then differentiate into spermatozoa and ova to produce offspring. ...
Cell & Microbiology
Nov 11, 2022
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Scientists have known that sex-determination in vertebrates happens in the germ cells, a body's reproductive cells, and the somatic cells, the cells that are not reproductive cells. Yet they have not fully understood the ...
Plants & Animals
Sep 9, 2022
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72
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights ...
Cell & Microbiology
May 7, 2024
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Germ cells, the reproductive cells that eventually become eggs and sperm, are set aside early in embryonic development, when the embryo is just a hollow ball of cells called the gastrula. This means that the cells transferring ...
Cell & Microbiology
Nov 1, 2022
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During fruit fly embryo formation, primordial germ cells—the stem cells that will later form eggs and sperm—must travel from the far end of the embryo to their final location in the gonads. Part of the primordial germ ...
Cell & Microbiology
Sep 16, 2022
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Primordial germ cells (PGCs) are the first germ-cell population established during development. The survival of species is dependent upon PGCs in sexually reproducing organisms because they are the founder cells for the germline.
Cell & Microbiology
May 10, 2022
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58
Totipotency is the ability of a cell to develop into an individual through elaborate processes of embryogenesis and is created during the development of the precursors of sperm and eggs, which are called germline cells. Understanding ...
Cell & Microbiology
Aug 22, 2022
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18
Female babies are born with a full set of egg precursors in their ovaries, yet the molecular mechanism by which these cells proliferate during embryonic development was unclear. Now, using a mouse model created at A*STAR, ...
Cell & Microbiology
Jun 14, 2017
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