Researchers reveal DNA repair mechanism
A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Cell & Microbiology
May 16, 2023
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100
News tagged with polymerase
New breathalyzer for disease sniffs out COVID in real-time, could be used to detect cancer, lung disease
With each breath, humans exhale more than 1,000 distinct molecules, producing a unique chemical fingerprint or "breathprint" rich with clues about what's going on inside the body.
Analytical Chemistry
May 10, 2023
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126
DNA microcapsules: Scaling up the future of data storage
Storing data in DNA sounds like science fiction, yet it lies in the near future. Professor Tom de Greef expects the first DNA data center to be up and running within five to ten years. Data won't be stored as zeros and ones ...
Bio & Medicine
May 4, 2023
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69
Researchers uncover the first steps driving antibiotic resistance
Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide. Looking to contribute a solution to this growing problem, ...
Cell & Microbiology
Mar 31, 2023
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75
Detecting rapidly mutating bacteria and viruses with AutoPLP
As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.
Biochemistry
Feb 15, 2023
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36
Researchers use cryo-electron microscopy to reveal structural changes that temporarily shut down RNA synthesis
Precise control of gene expression—ensuring that cells make the correct components in the right amount and at the right time—is vital for all organisms to function properly. Cells must regulate how genes encoded in the ...
Cell & Microbiology
Feb 10, 2023
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70
Using environmental DNA for to survey the populations of endangered species
Changes in river systems, overfishing and the appearance of new, invasive species can lead to a drastic decline in the number of native fish inhabiting aquatic ecosystems. In the Ashida river basin in Japan, the bitterling ...
Ecology
Feb 7, 2023
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5
Gone fishing: Highly accurate test for common respiratory viruses uses DNA as 'bait'
Cambridge researchers have developed a new test that "fishes" for multiple respiratory viruses at once using single strands of DNA as bait and gives highly accurate results in under an hour.
Bio & Medicine
Jan 16, 2023
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67
An electrochemical biosensor for antibody detection
The quantitative detection of specific antibodies in complex samples such as blood can provide information on many different diseases but usually requires a complicated laboratory procedure. A new method for the rapid, inexpensive, ...
Biochemistry
Jan 13, 2023
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41
How did investigators use DNA profiling to identify the suspect in the Idaho student killings?
Police investigating the murders of four University of Idaho students have said they used DNA to link evidence found at the crime scene to their suspect, 28-year-old Bryan Kohberger.
Other
Jan 9, 2023
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4
Polymerase
A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.
It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.
One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.
Other well-known polymerases include:
This text uses material from Wikipedia, licensed under CC BY-SA
