Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, differentiation, and survival by ...
Cell & Microbiology
Aug 9, 2022
0
8
Two tiny mutations in the genome of cattle likely cause some animals to be significantly more susceptible to digital dermatitis, an extremely painful disease that is widespread in cattle kept indoors. The two candidate genes ...
Plants & Animals
Aug 4, 2022
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3
In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, ...
Evolution
Jun 8, 2022
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421
Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.
Molecular & Computational biology
May 6, 2022
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203
Genetic information is stored in DNA and transcribed as mRNA. The mRNA is usually translated into proteins. However, it has long been known that mRNA can also be reverse transcribed to DNA and integrated back into the genome. ...
Evolution
Feb 2, 2021
0
63
Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria. The system is based on tiny, functionalized cantilevers that bend ...
Cell & Microbiology
Dec 7, 2020
0
6
Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without causing double-stranded DNA breaks, hold great promise for gene therapy in human disease and trait improvement in crop ...
Biotechnology
Jul 27, 2020
0
5
Whilst most organisms try to stop their DNA from mutating, scientists from the UK and China have discovered that a common fungus found on bread actively mutates its own DNA as a way of fighting virus-like infections.
Biotechnology
Jun 22, 2020
0
112
Many genetic and breeding studies have shown that point mutations and indels (insertions and deletions) can alter elite traits in crop plants. Although nuclease-initiated homology-directed repair (HDR) can generate such changes, ...
Biotechnology
Mar 16, 2020
0
32
A typo appearing in the draft of a novel is no great calamity. Nature, however, is often less forgiving of errors. A change in just one letter of the genetic code can have catastrophic consequences for human health.
Biotechnology
Feb 27, 2020
0
15
