Uncovering the secret of insulin growth factor ternary complex

Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, differentiation, and survival by ...

The underestimated mutation potential of retrogenes

Genetic information is stored in DNA and transcribed as mRNA. The mRNA is usually translated into proteins. However, it has long been known that mRNA can also be reverse transcribed to DNA and integrated back into the genome. ...

Quick and sensitive identification of multidrug-resistant germs

Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria. The system is based on tiny, functionalized cantilevers that bend ...

Bread mould avoids infection by mutating its own DNA

Whilst most organisms try to stop their DNA from mutating, scientists from the UK and China have discovered that a common fungus found on bread actively mutates its own DNA as a way of fighting virus-like infections.

Scientists optimize prime editing for rice and wheat

Many genetic and breeding studies have shown that point mutations and indels (insertions and deletions) can alter elite traits in crop plants. Although nuclease-initiated homology-directed repair (HDR) can generate such changes, ...

SNIPRs take aim at disease-related mutations

A typo appearing in the draft of a novel is no great calamity. Nature, however, is often less forgiving of errors. A change in just one letter of the genetic code can have catastrophic consequences for human health.

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