Understanding genetic diversity of bacteriophages

Over the last seven years, thousands of undergraduate students have joined the effort to sequence and analyze the genomes of bacteria-infecting viruses as part of the Howard Hughes Medical Institute's Science Education Alliance ...

Phages work together to suppress CRISPR bacterial immunity

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair ...

Inflammation awakens sleepers

The inflammatory response that is supposed to ward off pathogens that cause intestinal disease makes this even worse. This is because special viruses integrate their genome into Salmonella, which further strengthens the pathogen.

Cataloging nature's hidden arsenal: Viruses that infect bacteria

Scientists are continually searching for new and improved ways to deal with bacteria, be it to eliminate disease-causing strains or to modify potentially beneficial strains. And despite the numerous clever drugs and genetic ...

Cholera strain becomes unexpectedly resistant to infection by phages

Graduate student Kristen LeGault and assistant professor Kimberley Seed, both in the Department of Plant and Microbial Biology, specialize in the evolution of human pathogens and the viruses that infect bacteria, known as ...

Important role of prokaryotic viruses in sewage treatment

Prokaryotic viruses (phages) existing in activated sludge (AS), a biological treatment process widely used in wastewater treatment plants (WWTPs), act to regulate the composition of microbial community in the activated sludge. ...

Virus therapy to attack superbugs

VIRUSES specifically designed to battle superbugs are being trialled in a South Australian hospital.

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