University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use ...
Cell & Microbiology
May 2, 2024
0
27
Self-assembling molecules that spontaneously organize themselves to form complex structures are common in nature. For example, the tough outer layer of insects, called the cuticle, is rich in proteins that can self-assemble.
Bio & Medicine
Apr 26, 2024
0
21
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging ...
Biochemistry
Feb 14, 2024
0
102
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...
Biochemistry
Dec 28, 2023
0
203
A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power ...
Biochemistry
Aug 23, 2023
0
78
In a cutting-edge discovery, published in the Journal of the American Chemical Society, Florey scientists have solved a long-standing problem: the need for an affordable, simple way to make peptide-based drugs that hold their ...
Biochemistry
Jul 17, 2023
0
61
Plants engineered to produce therapeutic peptides could provide a cost-effective and sustainable platform for manufacturing drugs.
Cell & Microbiology
May 10, 2023
0
19
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
0
38
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
0
36
A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
