An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat ...
Bio & Medicine
Nov 4, 2019
2
1095
About one in four older adults suffers from chronic pain. Many of those people take medication, usually as pills. But this is not an ideal way of treating pain: Patients must take medicine frequently, and can suffer side ...
Bio & Medicine
Aug 5, 2014
0
0
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
0
20
New substances that activate adrenalin receptors instead of opioid receptors have a similar pain relieving effect to opiates, but without the negative aspects such as respiratory depression and addiction.
Biochemistry
Oct 4, 2022
0
33
A tiny snail may offer an alternative to opioids for pain relief. Scientists at the University of Utah have found a compound that blocks pain by targeting a pathway not associated with opioids. Research in rodents indicates ...
Biochemistry
Feb 20, 2017
12
2827
Anyone who has ever bitten unknowingly into a red hot chili pepper remembers the unhappy result – burning, painful sensations that make one's mouth feel as though it has caught on fire. Yet the very chemical that causes ...
Biochemistry
Apr 21, 2015
0
423
When considering laws, workplace policies or school rules, one might take notice of whom they impact. New research from the University of New Mexico has found whether it's interventions to reduce workplace bullying, help ...
Social Sciences
May 10, 2023
0
15
Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable. Moreover, pain medications can have side-effects such as dependence and ...
Molecular & Computational biology
Mar 4, 2023
0
53
Since the early days of social media, there has been excitement about how data traces left behind by users can be exploited for the study of human behaviour. Nowadays, reseachers who were once restricted to surveys or experiments ...
Social Sciences
Jul 12, 2021
0
4
According to a multidisciplinary study at the University of Oulu, contemporary Finns' vertebrae have not grown in the same proportion to body size compared to people who lived 200 to 500 years ago. The smaller size of vertebrae ...
Evolution
Feb 12, 2020
0
52
