In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into oocyte-like cells that ...
Biotechnology
Dec 16, 2020
0
82
The error-free division of mouse oocytes—the precursors of eggs—needs kinetochores that are rich in a specific microtubule crosslinker, RIKEN researchers have discovered. This finding could explain why the division of ...
Plants & Animals
Jul 31, 2020
0
19
By introducing a chemical cocktail to granulosa cells, researchers in China induced the cells to transform into functional oocytes in mice. Once fertilized, these oocytes were then successfully able to produce healthy offspring, ...
Cell & Microbiology
Dec 24, 2019
12
481
In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until recently, regulators ...
Biotechnology
Nov 29, 2018
0
55
The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions. The two primary methods ...
Cell & Microbiology
Jul 3, 2018
0
4
A longstanding obstacle to the market for bovine embryos is lipid accumulation in oocytes. Researchers have now described a hitherto unknown mechanism of lipid accumulation in oocytes that limits the success of in vitro production ...
Other
Aug 22, 2017
0
1
Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
0
4
Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional building blocks required to support a growing embryo. ...
Cell & Microbiology
Jan 28, 2016
0
20
The protein necessary for fertility in both sexes performs distinctly different roles in male and female gametes, according to a groundbreaking study, which included researchers from the University of Georgia College of Veterinary ...
Cell & Microbiology
Jan 30, 2015
0
70
Muhammad Anzar, a research scientist for Agriculture and Agri-Food Canada, is an expert in cryopreservation—you know, freezing living matter to cheat death.
Biochemistry
Jan 19, 2015
0
30
