'Semi-synthetic' bacteria churn out unnatural proteins

Synthetic biologists seek to create new life with forms and functions not seen in nature. Although scientists are a long way from making a completely artificial life form, they have made semi-synthetic organisms that have ...

Scientists identify new virus-killing protein

A new protein called KHNYN has been identified as a missing piece in a natural antiviral system that kills viruses by targeting a specific pattern in viral genomes, according to new findings published today in eLife. Studying ...

Global data resource shows genetic diversity of chickens

A total of 174 chicken breeds are described in a publicly accessible database which scientists from the University of Göttingen and the Friedrich Loeffler Institute in Neustadt-Mariensee have built up in recent years with ...

Dark centers of chromosomes reveal ancient DNA

Geneticists exploring the dark heart of the human genome have discovered big chunks of Neanderthal and other ancient DNA. The results open new ways to study both how chromosomes behave during cell division and how they have ...

DNA base editing induces substantial off-target RNA mutations

In a study published in Nature on June 10, researchers from Dr. Yang Hui's Lab at the Institute of Neuroscience of the Chinese Academy of Sciences (CAS), and collaborators from the CAS-MPG Partner Institute for Computational ...

Scientists create new standard genome for heavily studied worm

A new Cornell University-led study finds that the genome for a widely researched worm, on which countless studies are based, was flawed. Now, a fresh genome sequence will set the record straight and improve the accuracy of ...

Genetic testing has a data problem. New software can help.

In recent years, the market for direct-to-consumer genetic testing has exploded. The number of people who used at-home DNA tests more than doubled in 2017, most of them in the U.S. About 1 in 25 American adults now know where ...

Cellular microRNA detection with miRacles

MicroRNAs (miRNAs) are short noncoding regulatory RNAs that can repress gene expression post-transcriptionally and are therefore increasingly used as biomarkers of disease. Detecting miRNAs can be arduous and expensive as ...

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Nucleotide

Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling (cGMP and cAMP), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, FAD, FMN, and NADP+). Nucleotide derivatives such as the nucleoside triphosphates play central roles in metabolism, in which capacity they serve as sources of chemical energy (ATP and GTP).

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