DNA repair mechanism further elucidated in cryo-electron microscopy experiment
Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair.
Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair.
Molecular & Computational biology
May 28, 2024
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40
Humans, Homo sapiens, have unique features compared with other closely related hominin species and primates, including the shape of the base of the skull. The evolutionary changes underlying these features were significant ...
Evolution
Apr 17, 2024
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57
Curly—or Karelian—birch is a mysterious tree with a patterned wood texture and a bizarre trunk shape. Unlike the elegant white-stemmed traditional birch, the Karelian one may seem unsightly at first glance: It is a low-growing, ...
Plants & Animals
Mar 22, 2024
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9
For the first time, scientists from the University of Cologne (UoC) have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory, which could be used as artificial ...
Biotechnology
Mar 8, 2024
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89
The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it's possible to add more letters to this alphabet ...
Biotechnology
Dec 14, 2023
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64
DNA sequencing technology, i.e., determining the order of nucleotide bases in a DNA molecule, is central to personalized medicine and disease diagnostics, yet even the fastest technologies require hours, or days, to read ...
Biochemistry
Jul 31, 2023
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83
As life expectancy increases worldwide, age-associated diseases such as osteoporosis are having an increasing impact.
Biochemistry
Jul 19, 2023
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34
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic ...
Cell & Microbiology
Jul 10, 2023
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92
Humans contain multitudes. Each person on the planet contains enough DNA to stretch to Pluto—several times.
Molecular & Computational biology
Jun 29, 2023
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15
Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair damaged DNA may induce ...
Molecular & Computational biology
Jun 12, 2023
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31