In a landmark study to be published in the journal Nature, scientists have been able to create the first picture of genetic processes that happen inside every cell of our bodies. Using a 3-D visualization method called X-ray ...
Biochemistry
Aug 25, 2010
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0
A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...
Cell & Microbiology
Jul 12, 2018
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128
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
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9
Until human genes are activated, they are blocked by structures known as nucleosomes, components that serve to package DNA inside cells.
Biotechnology
May 14, 2018
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144
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure ...
Cell & Microbiology
Apr 26, 2024
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85
The DNA in our cells is folded into millions of small packets, like beads on a string, allowing our two-meter linear DNA genomes to fit into a nucleus of only about 0.01 mm in diameter. However, these molecular beads, called ...
Cell & Microbiology
Nov 5, 2015
1
27
A fertilized human egg develops into multiple tissues, organs and about 200 distinct cell types. Each cell type has the same genes, but they are expressed differently during development and in mature cells.
Cell & Microbiology
Aug 30, 2017
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199
Chromatin inheritance during cell division involves the replication of DNA and assembly of nucleosomes onto the replicated DNA, because passage of the DNA replication fork disrupts nucleosomes on the DNA. Half of the histones ...
Cell & Microbiology
Aug 25, 2023
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101
The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are ...
Biotechnology
Nov 21, 2019
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126
In plants and animals, the basic packaging units of DNA, which carry genetic information, are the so-called nucleosomes. A nucleosome consists of a segment of DNA wound around eight proteins known as histones.
Bio & Medicine
May 10, 2024
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26
