Biologists design a plug-and-play controller for gene expression

Researchers from two University of Texas System institutions have engineered biological components that can rewire genetic response pathways, creating a template for designing new cellular behaviors with wide-ranging potential ...

Protein production efficiency can be predicted by gene sequence

Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities of all proteins ...

Unexpected finding in the cell's power plant

Researchers at Karolinska Institutet have discovered that the protein complex RNase P in the cell's mitochondria behaves differently than previously thought. The findings, published in Nucleic Acids Research, give important ...

Start codons in DNA may be more numerous than previously thought

For decades, scientists working with genetic material have labored with a few basic rules in mind. To start, DNA is transcribed into messenger RNA (mRNA), and mRNA is translated into proteins, which are essential for almost ...

Discovery of rules for CRISPR advance metabolic engineering

Discovery of rules that govern a variation of the CRISPR/Cas9 gene-editing method makes it possible to use living cells to manufacture valuable metabolic compounds like pharmaceuticals and nutraceuticals. Researchers at Rensselaer ...

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