Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma.
For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked ...
Biotechnology
Nov 5, 2019
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187
DNA is the molecule that contains all the genetic information necessary for the development and functioning of living organisms. It is organized in a structure called "chromatin," which is found inside the nucleus of cells. ...
Molecular & Computational biology
Jun 13, 2024
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27
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research ...
Cell & Microbiology
May 3, 2024
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66
G-quadruplexes (G4), which are special structures in DNA and RNA that play a crucial role in cells, have been associated with cancers and neurological diseases. A research team from City University of Hong Kong (CityU) recently ...
Biotechnology
Mar 21, 2024
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0
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
0
66
A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been published in Nucleic Acids ...
Molecular & Computational biology
Nov 9, 2023
0
183
Researchers in Carnegie Mellon University's Department of Chemistry have developed a reagent that opens new possibilities for creating DNA and RNA-based materials that could be used in ultra-stable and smart sensors for biomedical ...
Biochemistry
Sep 4, 2023
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67
The human gut hosts a complex ecosystem comprising an intricate plasmidome with abundant undiscovered plasmids, driving horizontal gene transfer events.
Cell & Microbiology
Jun 28, 2023
0
27
The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting ...
Cell & Microbiology
May 16, 2023
0
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