Fluorescent microscopy makes use of molecules, such as green fluorescent protein (GFP), that emit colored light when illuminated with light of a specific wavelength. Molecules like GFP can be used to label proteins of interest ...
Biochemistry
Sep 21, 2010
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(PhysOrg.com) -- UC Berkeley researchers Karsten Weis, Jan Liphardt, and colleagues have used fluorescent probes called quantum dots to determine which molecules get into the nucleus via its nano-pores and which get kicked ...
Bio & Medicine
Sep 2, 2010
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(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.
Cell & Microbiology
Oct 27, 2009
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(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...
Cell & Microbiology
Sep 29, 2009
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(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...
Cell & Microbiology
Aug 18, 2009
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Like guards controlling access to a gated community, nuclear pore complexes are communication channels that regulate the passage of proteins and RNA to and from a cell's nucleus. Recent studies by researchers at the Salk ...
Jan 22, 2009
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In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing ...
Cell & Microbiology
Jul 6, 2020
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In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...
Cell & Microbiology
Jun 12, 2019
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All creatures of the animal kingdom share one thing: the nuclear membrane. Wrapping the genetic core of the cell, this membrane, together with all the attached proteins, plays a vital role in biological functions. Despite ...
Cell & Microbiology
Sep 8, 2017
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Nuclear pore complexes are tiny channels where the exchange of substances between the cell nucleus and the cytoplasm takes place. Scientists at the University of Basel report on startling new research that might overturn ...
Cell & Microbiology
Sep 4, 2017
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