Motor proteins haul precious cargo in neurons. How can we control their movement?
Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks.
Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks.
Cell & Microbiology
Jan 20, 2022
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58
Proteins, the ubiquitous workhorses of biochemistry, are huge molecules whose function depends on how they fold into intricate structures. To understand how these molecules work, researchers use computer modeling to calculate ...
General Physics
Dec 5, 2017
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238
The brain is the most temperature-sensitive organ in the body. Even small deviations in brain temperature are capable of producing profound effects—including behavioral changes, cell toxicity, and neuronal cell death. The ...
Optics & Photonics
Jul 20, 2016
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18
Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for termination. This cell helps determine ...
Cell & Microbiology
Apr 8, 2016
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461
In what they are calling a new direction in the study of Alzheimer's disease, UC Santa Barbara scientists have made an important finding about what happens to brain cells that are destroyed in Alzheimer's disease and related ...
Biochemistry
Jun 6, 2011
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Researchers from the University of Eastern Finland and the University of Montreal (Canada) have discovered that a micro-protein, which they named Nrs1, supports cell division and proliferation when nutrients are scarce. This ...
Molecular & Computational biology
Mar 4, 2022
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8
Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. GSDMD-deficient cells are, however, susceptible to caspase-1-mediated cell death. Researchers at Kanazawa University and others discovered ...
Cell & Microbiology
Jul 5, 2019
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1
A protein linked to Parkinson's disease may cause neurodegeneration by inhibiting autophagy -- the process in which cells digest some of their contents -- according to a study in the September 20 issue of the Journal of Cell ...
Cell & Microbiology
Sep 20, 2010
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0
Recent studies have shown that the mitochondrial peptide Humanin (HN) protects against neuronal cell death such as happens in Alzheimer's disease. Now, in a study presented April 22 at Experimental Biology 2009 in New Orleans, ...
Cell & Microbiology
Apr 22, 2009
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0
Stem cell derived neurons may allow scientists to determine whether breakdowns in the transport of proteins, lipids and other materials within cells trigger the neuronal death and neurodegeneration that characterize Alzheimer's ...
Cell & Microbiology
Dec 9, 2009
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