Embryo's early development revealed in a dish

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these ...

Flavins keep a handy helper in their pocket

In human cells, vitamins often serve as the precursors of cofactors—non-proteins that are an essential part of enzymes. Among them are the flavins, derived from vitamin B2.

Tissue mechanics essential for cell movement

Cells that form facial features need surrounding embryonic tissues to stiffen so they can move and develop, according to new UCL-led research.

History of cells told through MEMOIR

Researchers have developed a new method for reading the history and "family trees" of cells. Called MEMOIR, or Memory by Engineered Mutagenesis with Optical In situ Readout, the technique can record the life history of animal ...

Cadherin-11 plays role in cell migration

Cadherins are part of the protein family of adhesion molecules. Just like mortar between the bricks in a wall, they ensure that cells stay together, preventing them from breaking away and migrating from a group of cells. ...

DNA breaks in nerve cells' ancestors cluster in specific genes

The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston ...

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