How the TB bacterium develops rapid resistance to antibiotics

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a ...

Antibacterial prodrug by targeting intracellular metabolite

National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...

Blocking iron transport could stop tuberculosis

One of the most devastating pathogens that lives inside human cells is Mycobacterium tuberculosis, the bacillus that causes tuberculosis. According to the World Health Organization, 1.5 million people died in 2019 from this ...

Wily tuberculosis bacteria can vary its diet to infect you longer

Worldwide, approximately one in four people is infected by Mycobacterium tuberculosis and while overall New Zealand has relatively low rates of TB, Māori and Pacific people are eight times more likely to be affected than ...

Antacid helps tuberculosis bacteria to survive

In 2017, some 10 million people suffered from tuberculosis and 1.6 million died of the disease. One reason that infection with Mycobacterium tuberculosis is so difficult to treat is because the bacteria can hide inside immune ...

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