A sophisticated system of "social control" operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues. This system works through ...
Cell & Microbiology
Sep 26, 2017
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4
The original iPS cells were reprogrammed by transducing four genes: OCT3/4, SOX2, KLF4, and c-MYC. Later experiments would show that c-MYC can be replaced with MYCL. Both are MYC proteins and thus oncogenes, but animal experiments ...
Cell & Microbiology
Dec 21, 2021
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8
Most human tumours have one thing in common: They harbour drastically increased amounts of the so-called Myc proteins. Animal experiments show that such high Myc concentrations contribute to causing cancer. But Myc proteins ...
Biotechnology
Oct 17, 2017
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2
Why do healthy cells become malignant and proliferate uncontrollably? Scientists of the University of Würzburg have investigated the role of a special protein in this process and settled and old controversy.
Biochemistry
Aug 4, 2016
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6
Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail. However, this regenerative process must be tightly regulated by the body to ensure proper tissue organization ...
Cell & Microbiology
Mar 20, 2024
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1
Maize (Zea mays) is an important food, feed, and bioenergy crop that plays a pivotal strategic role in food security, while insect pests seriously affect the yield and quality of maize. Benzoxazinoids (BXDs) and volatile ...
Molecular & Computational biology
Nov 16, 2022
0
5
The germline is the cell lineage of an organism that passes on its genetic material to its progeny. Genetic damage to the germline can cause developmental defects and even death of that same progeny. It is thought that biological ...
Biotechnology
May 7, 2020
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4
A year ago, the Howe lab developed a plant that upended a common misconception that plants can defend or grow, but not both. Theirs could.
Biotechnology
Jul 11, 2017
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