MYC is the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering hope for a new era of treatments.
Biochemistry
Jan 11, 2024
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468
Given the important role in functioning as oncogenes or tumor suppressors, c-myc mRNA has emerged as a potential biomarker for cancer detection. In particular, abnormal expression of mRNAs is commonly observed at early stages ...
Bio & Medicine
Mar 24, 2016
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10
Induced pluripotent stem cells, or iPS cells, are a hot commodity right now in biology.
Cell & Microbiology
Sep 9, 2013
1
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The Innovation Center of NanoMedicine reported in ACS Nano together with the group of Prof. Yu Matsumoto of Otorhinolaryngology and Head and Neck Surgery and the group of Prof. Horacio Cabral of the Department of Bioengineering ...
Bio & Medicine
Feb 26, 2021
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43
One of the most common cancer-promoting genes, known as Myc, is also one of the most difficult to target with drugs. Scientists have long tried to develop drugs that block the Myc protein, but so far their efforts have not ...
Biochemistry
Mar 15, 2019
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122
Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into ...
Cell & Microbiology
Apr 10, 2018
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121
Several years ago, biologists discovered that regular body cells can be reprogrammed into pluripotent stem cells—cells with the ability to become any other type of cell. Such cells hold great promise for treating many human ...
Cell & Microbiology
Sep 13, 2012
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0
An international team of seven institutions from Spain and the US including the University of Valencia has discovered for the first time that the biological activity of the c-MYC gene is necessary for cell reprogramming, ...
Cell & Microbiology
Nov 30, 2018
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8
For decades, cancer researchers have longed for a way to target a set of proteins called transcription factors. While we've long known that tumors use these proteins to grow out of control, their unique configurations meant ...
Biotechnology
Nov 3, 2022
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14
Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell. The study, published in Nature Structural and Molecular ...
Cell & Microbiology
Nov 4, 2019
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24
