Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...
Biochemistry
Aug 10, 2021
0
680
Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells. In collaboration with the UMC Utrecht and Oncode Institute, they used a technique ...
Cell & Microbiology
Aug 9, 2021
0
998
Despite remarkable medical advances over the last years, cystic fibrosis remains the most prevalent lethal genetic disease. It is due to mutations in the CFTR protein which is normally required to maintain proper fluid balances ...
Biochemistry
Aug 3, 2021
0
359
A team of researchers working at the Francis Crick Institute has developed a way to find mutations in similar genome regions of cancer samples. In their paper published in the journal Nature Biotechnology, the group describes ...
An international team of researchers led by Kumamoto and Tokyo Universities (Japan) have shown that the L452R mutation of the SARS-CoV-2 spike protein, which is common to two mutant strains (Epsilon and Delta), is involved ...
Cell & Microbiology
Jul 20, 2021
0
5
Veterinarians at the University of California, Davis, have found that a cat's DNA alters how it responds to a life-saving medication used to treat hypertrophic cardiomyopathy, or HCM, a heart disease that affects 1 in 7 cats. ...
Veterinary medicine
Jul 6, 2021
0
6
One of the key mutations seen in the 'Alpha variant' of SARS-CoV-2—the deletion of two amino acids, H69/V70—enables the virus to overcome chinks in its armour as it evolves, say an international team of scientists.
Cell & Microbiology
Jun 29, 2021
1
39
A few males are enough to fertilize all the females. The number of males therefore has little bearing on a population's growth. However, they are important for purging bad mutations from the population. This is shown by a ...
Evolution
Jun 28, 2021
0
16
Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection. All current COVID-19 vaccines and antibody-based therapeutics were designed to disrupt ...
Cell & Microbiology
Jun 25, 2021
6
884
Thousands of years ago, archaic humans such as Neanderthals and Denisovans went extinct. But before that, they interbred with the ancestors of present-day humans, who still to this day carry genetic mutations from the extinct ...
Evolution
Jun 17, 2021
0
18
