New technology selects high-affinity proteins

Kobe University and the National Institute of Advanced Industrial Science and Technology (AIST) in Japan have developed a technology enabling the selection of proteins with a high affinity for drug target molecules (also ...

Researchers discover new way to form extracellular vesicles

Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals ...

Novel target for diabetes drug identified as ion exchanger

Nagoya University-led researchers use nematode worms as a model to identify a new target of the type 2 diabetes drug metformin; ion exchanger protein NHX-5 and its related protein in fruit flies are potential metformin targets, ...

M6P deficiency leaves B cells out of sorts

A group of white blood cells known as B cells, which play a key role in the human immune response, need a protein-targeting signal called mannose 6-phosphate (M6P) in order to proliferate, differentiate, and present immune ...

Embryo blood cells are stem cell–independent

The fetal liver is the major hematopoietic organ during the embryonic stage. It is generally believed that hematopoietic hierarchy in the fetal liver is established through the differentiation of fetal hematopoietic stem ...

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