Researchers shake up scientific theory on motor protein

(PhysOrg.com) -- An international team of scientists led by the University of Leeds has shed new light on the little-understood motor protein called dynein, thought to be involved in progressive neurological disorders such ...

Let's stretch... Scientists study myomesin protein

The proteins actin, myosin and titin are big players in the business of muscle contraction. Scientists at the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now examined another muscle protein – ...

Biophysics: Order in chaos

The process of skeletal muscle contraction is based around protein filaments sliding inside sarcomeres — the structural units of muscle fiber. Inside each sarcomere is a set of filament motors, which appear in different ...

Atomic model of tropomyosin bound to actin

New research sheds light on the interaction between the semi-flexible protein tropomyosin and actin thin filaments. The study, published by Cell Press on February 15th in the Biophysical Journal, provides the first detailed ...

New CRISPR method efficiently corrects DMD defect in heart tissue

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's ...

Pig stress syndrome linked to gene defect

Undergoing surgery, even a minor procedure, can be stressful for anyone. But for people who have malignant hyperthermia, a hereditary disease that's triggered by certain drugs used for general anesthesia, it can also be dangerous.

New insight into the regulation of stem cells and cancer cells

Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important ...

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