Learning from endangered zebra stem cells

Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and Wildlife Research Centre have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further ...

A missing genetic switch at the origin of embryonic malformations

Embryonic development follows delicate stages: For everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more ...

Skull birth defect detailed in cell-by-cell description

Contrary to the popular song, the neck bone is actually connected to one of 22 separate head bones that make up the human skull. These plate-like bones intersect at specialized joints called sutures, which normally allow ...

Recreating the earliest stages of life

In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos. The use of animal embryos is also subject to restrictions ...

Advanced mouse embryos grown outside the uterus

To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought ...

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