New advances in stem-cell derived mouse embryo model

Just two weeks after announcing the development of a mouse embryo model, complete with beating hearts and the foundations for a brain and other organs, from mouse stem cells, researchers in the laboratory of Magdalena Zernicka-Goetz, ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

'Synthetic embryo' breakthrough but growing human organs far off

Stem cell scientists say they have created "synthetic embryos" without using sperm, eggs or fertilization for the first time, but the prospect of using such a technique to grow human organs for transplantation remains distant.

The beginning of life: The early embryo is in the driver's seat

One often thinks that the early embryo is fragile and needs support. However, at the earliest stages of development, it has the power to feed the future placenta and instructs the uterus so that it can nest. Using blastoids, ...

Mouse stem cells for primitive endoderm established

Stem cells that give rise to the mouse yolk sac have been isolated and cultured in the lab for the first time by RIKEN researchers, raising the possibility of artificially creating mouse embryos from stem cells in the future.

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