Hook-on drugs: New delivery strategy for K-Ras disruption

"The strategy was to design the drug to be able to hook into the hole of the FTase and GGTase I, otherwise the surface of the proteins are too large and slippery," Dr. Junko Ohkanda of Shinshu University explains her strategy ...

Study probes interplay of proteins in type 2 diabetes

A hallmark of age-related diseases such as Parkinson's disease, type 2 diabetes, or Alzheimer's disease is the abnormal clumping of proteins in cells. In people with these conditions, these protein clumps can result in irregular ...

Using lasers to visualize molecular mysteries in our atmosphere

Invisible to the human eye, molecular interactions between gases and liquids underpin much of our lives, including the absorption of oxygen molecules into our lungs, many industrial processes and the conversion of organic ...

Single molecule magnet used as a scanning magnetometer

A team of researchers from the University of California and Fudan University has developed a way to use a single molecule magnet as a scanning magnetometer. In their paper published in the journal Science, the group outlines ...

How to pop open soft nanoparticles using sound waves

Ultrasound has long been an important tool for medical imaging. Recently, medical researchers have demonstrated that focused ultrasound waves can also improve the delivery of therapeutic agents such as drugs and genetic material. ...

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