Translating an RNA boosts its degradation, find researchers

In the cell, messenger RNAs—or mRNAs—are translated into proteins and eventually degraded, but the relationship between translation and mRNA decay remains cloudy. FMI researchers developed an innovative tool to control ...

This one-atom chemical reaction could transform drug discovery

Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production. Now, in a study recently published in Science, researchers ...

Distinguishing between right and left with magnets

Using a chiral superconductor, scientists at Institute for Molecular Science and Shizuoka University have demonstrated that the magnet can distinguish right and left forms of the chiral crystal despite the common belief that ...

Discovery of a cellular uptake pathway for larger drug molecules

Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...

Can AI transform the way we discover new drugs?

The world's aging population, the growing burden of chronic and infectious diseases, and the emergence of novel pathogens have made the need for new treatments more urgent than ever. Yet, discovering a new drug and bringing ...

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