The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical ...
Biochemistry
Mar 5, 2019
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24
Having absolute control of the activity of a molecule in an organism, or deciding when, where and how a drug is activated—these are some of the goals possible with so-called photoswitchable molecules, compounds that change ...
Materials Science
Mar 1, 2019
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92
The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...
Bio & Medicine
Feb 27, 2019
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53
Discovering and designing a new drug is one of the most challenging tasks in the biological sciences. It takes over 10 years and about US$2.6 billion to bring an average drug to market.
Computer Sciences
Feb 26, 2019
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8
Did you know that more than half of the drugs currently in use are chiral, potentially resulting in two different responses in the body? Chiral compounds are pairs of molecules that are mirror images of each other, just like ...
Materials Science
Feb 21, 2019
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6
Old molecules and new complexes: researchers at Hollings Cancer Center at the Medical University of South Carolina (MUSC) have discovered cell membrane complexes called ceramidosomes that may be a new target for drugs to ...
Biochemistry
Feb 13, 2019
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39
Researchers have designed a machine learning algorithm for drug discovery which has been shown to be twice as efficient as the industry standard, which could accelerate the process of developing new treatments for disease.
Biochemistry
Feb 11, 2019
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160
To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic-scale drug-cardiac cells ...
Biochemistry
Feb 7, 2019
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31
Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available ...
Biochemistry
Feb 6, 2019
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59
No, molecules do not actually have hands. But scientists refer to them in this way when looking at asymmetric molecules that are mirror images of one another and therefore are not superimposable. Whether a molecule is a "lefty" ...
Materials Science
Feb 4, 2019
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