A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.
Analytical Chemistry
Jun 7, 2024
0
0
The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression includes regions of ...
Cell & Microbiology
Jun 5, 2024
0
2
Scientists at the University of Wisconsin–Madison have developed the most sensitive method yet for detecting and profiling a single molecule—unlocking a new tool that holds potential for better understanding how the building ...
Analytical Chemistry
May 30, 2024
0
326
A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Bio & Medicine
May 29, 2024
0
29
A team of researchers has recently demonstrated the utility of employing a previously established screening system to probe the interactions between small molecules and RNA. Their study is published in Communications Chemistry.
Biochemistry
May 21, 2024
0
6
An increasing number of bacteria have become resistant to many commonly used antibiotics. Researchers from Bochum have discovered a fresh opportunity for a potential active molecule whose predecessor was rejected. By studying ...
Biochemistry
May 16, 2024
0
1
Collaborating researchers have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs—specifically artemisinin (ART)—through a cellular process called transfer ribonucleic acid ...
Cell & Microbiology
May 16, 2024
0
30
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit ...
Biochemistry
May 8, 2024
0
13
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
Biochemistry
Apr 25, 2024
0
54
Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests.
Analytical Chemistry
Apr 24, 2024
0
1
