Scientists from the University of Washington have designed custom proteins that can switch between two fully structured conformations. By coupling this molecular motion with a binding event, these proteins serve as biological ...
Biotechnology
Aug 23, 2023
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3
As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking. A grassroots movement ...
Cell & Microbiology
Aug 21, 2023
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0
Northwestern Medicine investigators have discovered that mitochondria regulate essential cellular signaling for the development of epithelial cells in the lungs, cells which are crucial for the exchange of oxygen and carbon ...
Cell & Microbiology
Aug 10, 2023
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4
Most prokaryotes have never been isolated in pure culture and cannot be named under the International Code of Nomenclature of Prokaryotes (ICNP). However, many studies have described uncultured bacteria and archaea though ...
Cell & Microbiology
Jul 24, 2023
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3
How active compounds affect RNA and thus the expression of genes is of great interest for the development of potential therapeutics. Innsbruck chemists have now used a method they recently developed to study the binding of ...
Biochemistry
Jul 20, 2023
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28
Understanding the molecular mechanism that triggers disease is essential for identifying new treatments. Cholera, a disease caused by the bacterium Vibrio cholerae, is no exception.
Cell & Microbiology
Jul 13, 2023
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76
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin have revealed how cells accelerate changes to their identity, ...
Cell & Microbiology
Jun 27, 2023
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58
In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes ...
Cell & Microbiology
Apr 28, 2023
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3
In a study recently published in the journal ACS Nano, researchers from Kanazawa University, Kanazawa, Japan, collaborating with University of Washington, Seattle, U.S., used frequency modulated atomic force microscopy to ...
Bio & Medicine
Mar 27, 2023
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30
Before 2020, when my friends and acquaintances asked me what I study as a molecular biologist, their eyes would inevitably glaze over as soon as I said "RNA." Now, as the COVID-19 pandemic has shown the power and promise ...
Cell & Microbiology
Mar 6, 2023
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