Using computer-engineered DNA to study cell identities

All the cells in our body have the same genetic code, and yet they can differ in their identities, functions and disease states. Telling one cell apart from another in a simple manner, in real time, would prove invaluable ...

CRISPR off-switches: A path towards safer genome engineering?

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved ...

Missing gene in mouse sperm could explain infertility

Mice lacking a certain gene are unable to produce offspring because their sperm lack the connection between the tail and the head. A new thesis from the University of Gothenburg indicates a probable cause of male infertility.

New human gene cluster sequence discovered

Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...

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