How much (DNA) damage can a cancer cell tolerate?

A new study led by Claus M. Azzalin, group leader at Instituto de Medicina Molecular João Lobo Antunes- iMM and published today in the Proceedings of the National Academy of Sciences (PNAS) shows, for the first time, that ...

Prions: New possible therapeutic target discovered

Prion diseases, such as bovine spongiform encephalopathy ("mad cow disease"), are lethal neurodegenerative infectious diseases that affect humans and other mammals and for which there is currently no cure.

Dense liquid droplets act as cellular computers

An emerging field explores how groups of molecules condense together inside cells, the way oil droplets assemble and separate from water in a vinaigrette.

New technique improves proteoform imaging in human tissue

Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed a new imaging technique that increases the detection of ...

From wound healing to regeneration

The phenomenon of regeneration was discovered over 200 years ago in the freshwater polyp Hydra. Until now, however, it was largely unclear how the orderly regeneration of lost tissues or organs is activated after injury. ...

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