Related topics: protein · cells · cancer cells · genes · chromosomes

Self-regulation of an enzyme with critical cellular functions

The lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate ...

Study identifies how blood stem cells maintain their fate

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical ...

There's more than one way to grow a baby

In his 1989 book Wonderful Life, evolutionary biologist Stephen Jay Gould famously argued that, if we could "replay the tape," life on Earth would evolve to be fundamentally different each time.

Potent alpaca nanobodies neutralize SARS-CoV-2 variants

Researchers at Karolinska Institutet in Sweden have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants. The approach led to the discovery of ...

Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

Cavefish modulate lipid metabolism to adapt to life in caves

The Sinocyclocheilus represents a rare freshwater teleost genus endemic to China. With widespread drying associated with the aridification of China during the late Miocene and Pliocene, Sinocyclocheilus began to seek refuge ...

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