How chemical modifications on DNA keep genes silent

Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...

Aging-emulating biosystem derived from hTSCs

A research team from the Center for Translational Stem Cell Biology (CTSCB) under the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has developed the world's first cellular system that can be used to rapidly ...

Decoding apples: Nitrogen's role in shaping fruit sugar content

Apple quality and yield are significantly affected by nitrogen levels in the soil, which influence various biochemical processes. Insufficient nitrogen can result in poor fruit quality, while excessive nitrogen leads to environmental ...

Famine fear won't sway minds on GM crops

A sack-hauling time traveler from the 21st century lands in an Irish potato field in 1849, just before a terrible famine, and asks: If you thought genetically modified (GM) potatoes could avert late blight disease, spare ...

Dual systems key to keeping chromosomes intact

USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable – while it is being unzipped for replication.

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