How to precisely edit mitochondrial DNA
Scientists can now precisely edit the genes inside mitochondria, the tiny energy factories inside of cells.
Biotechnology
Jul 8, 2020
1
294
News tagged with mitochondrial mutations
Tracking inheritance of human mitochondrial DNA
New insight into how genetic information stored in human mitochondria is passed from one generation to the next could have important implications for genetic counseling of women planning pregnancies, according to a study ...
Biotechnology
Nov 18, 2019
0
300
Ancient penguin DNA raises doubts about accuracy of genetic dating techniques
Penguins that died 44,000 years ago in Antarctica have provided extraordinary frozen DNA samples that challenge the accuracy of traditional genetic aging measurements, and suggest those approaches have been routinely underestimating ...
Evolution
Nov 10, 2009
16
0
Uncovering hidden mitochondrial mutations in single cells
A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...
Cell & Microbiology
Apr 13, 2023
0
45
Ancient DNA from medieval Germany tells origin story of Ashkenazi Jews
Excavating ancient DNA from teeth, an international group of scientists peered into the lives of a once thriving medieval Ashkenazi Jewish community in Erfurt, Germany. The findings, shared today in the journal Cell, show ...
Archaeology
Nov 30, 2022
0
2337
Research team first to develop 3D structure of twinkle protein
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
0
80
Are egg cells in aging primates protected from mutations?
New mutations occur at increasing rates in the mitochondrial genomes of developing egg cells in aging rhesus monkeys, but the increases appear to plateau at a certain age and are not as large as those seen in non-reproductive ...
Molecular & Computational biology
Apr 4, 2022
0
252
Biologists trace plants' steady mitochondrial genomes to a gene found in viruses, bacteria
One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat. After all, they have their own genome—a set of DNA-containing chromosomes—completely separate from the ...
Plants & Animals
Jul 9, 2020
0
67
Advanced sequencing technology provides new insights into human mitochondrial diseases
The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic ...
Molecular & Computational biology
Oct 19, 2018
0
29
Digging deep into distinctly different DNA
A University of Queensland discovery has deepened our understanding of the genetic mutations that arise in different tissues, and how these are inherited.
Cell & Microbiology
Jan 22, 2018
0
37
