Cancers, degenerative diseases: deregulation of our cells' internal communication pathways is at the root of many conditions. Microtubules—microscopic protein filaments—play a crucial role in controlling these exchanges. ...
Cell & Microbiology
Sep 5, 2023
0
25
Active matter is any collection of materials or systems composed of individual units that can move on their own, thanks to self-propulsion or autonomous motion. They can be of any size—think clouds of bacteria in a petri ...
General Physics
Sep 4, 2023
1
547
Researchers at the Center for Genomic Regulation (CRG) have discovered how proteins work in tandem to regulate "treadmilling," a mechanism used by the network of microtubules inside cells to ensure proper cell division. The ...
Cell & Microbiology
Aug 24, 2023
0
88
Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it ...
Biochemistry
Jun 29, 2023
0
45
Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment. During cell division, for instance, these cables latch onto chromosomes and ...
Cell & Microbiology
May 1, 2023
0
20
In a multidisciplinary study newly published in the Journal of Cell Biology, the Barral group (D-BIOL/IBC) together with the Steinmetz group (PSI) and the Stelling group (D-BSSE), sheds light on how the motor domain of the ...
Cell & Microbiology
Apr 28, 2023
0
11
Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare the cell for cell ...
Cell & Microbiology
Mar 9, 2023
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61
Researchers led by Dr. Jens Lüders at IRB Barcelona have discovered a key role played by the ch-TOG protein in the initiation of microtubule assembly during the interphase stage of the cell cycle—the phase in which cells ...
Cell & Microbiology
Jan 26, 2023
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10
Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers from the Okayama University reported that microtubules are ...
Cell & Microbiology
Jan 18, 2023
0
3
Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue. Clinging to the ends of filaments called microtubules, ...
Cell & Microbiology
Dec 19, 2022
0
12
Microtubules are a component of the cytoskeleton. These rope-like polymers of tubulin can grow as long as 25 micrometers and are highly dynamic. The outer diameter of microtubule is about 25 nm. Microtubules are important for maintaining cell structure, providing platforms for intracellular transport, forming the spindle during mitosis, as well as other cellular processes. There are many proteins that bind to the microtubule, including motor proteins such as kinesin and dynein, severing proteins like katanin, and other proteins important for regulating microtubule dynamics.
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