Protein linked to cancer acts as a viscous glue in cell division

An over-abundance of the protein PRC1, which is essential to cell division, is a telltale sign in many cancer types, including prostate, ovarian, and breast cancer. New research, published online today in Developmental Cell, ...

Biologists unravel tangled mystery of plant cell growth

When cells don't divide into proper copies of themselves, living things fail to grow as they should. For the first time, scientists now understand how a protein called TANGLED1 can lead to accurate cell division in plants.

How to build better highways in plants

As a plant grows, it moves cellular material from its version of manufacturing sites to the cell wall construction zone. Transporter proteins, called motor proteins, are thought to move these cell wall cargo via a complex ...

Stable conditions during cell division

Errors during cell division can trigger the development of cancer. No wonder that this central process is controlled by multiple regulators and guards. Alex Bird's research group at the Max Planck Institute of Molecular Physiology ...

Lane change in the cytoskeleton

Many amphibians and fish are able to change their color in order to better adapt to their environment. Munich-based scientists have now investigated the molecular mechanisms in the cytoskeleton necessary for this and revealed ...

How plants are built to be strong and responsive

Organised cellulose fibres allow plants to grow, support themselves and store fixed carbon from the atmosphere. Wood and dietary fibre is largely made of cellulose, and coal is derived from cellulose synthesised millions ...

Self-assembled artificial microtubule like LEGO building blocks

Simple LEGO bricks can be assembled to more complicated structures, which can be further associated into a wide variety of complex architectures, from automobiles, rockets, and ships to gigantic castles and amusement parks. ...

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Microtubule

Microtubules are a component of the cytoskeleton. These rope-like polymers of tubulin can grow as long as 25 micrometers and are highly dynamic. The outer diameter of microtubule is about 25 nm. Microtubules are important for maintaining cell structure, providing platforms for intracellular transport, forming the spindle during mitosis, as well as other cellular processes. There are many proteins that bind to the microtubule, including motor proteins such as kinesin and dynein, severing proteins like katanin, and other proteins important for regulating microtubule dynamics.

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