A new molecular player involved in T cell activation

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell activation, a molecular complex ...

Visualizing 'unfurling' microtubule growth

Living cells depend absolutely on tubulin, a protein that forms hollow tube-like polymers, called microtubules, that form scaffolding for moving materials inside the cell. Tubulin-based microtubule scaffolding allows cells ...

Keeping our cells stable: A closer look at microtubules

Microtubules help to regulate cell structure. A group of Japanese researchers have used cryo-electron microscopy to shed light on how a certain protein keeps microtubules stable and regulates microtubule-based transport within ...

Petry finds missing ingredient to spark the fireworks of life

Most people can name at least a few bones of the human body, but not many know about the cytoskeleton within our cells, let alone the "microtubules" that give it its shape. Now, a group of Princeton researchers has resolved ...

Key protein in sperm tail assembly identified

A study published in the Journal of Cell Biology focuses on the development of the sperm tail, the structure that enables sperm cells to swim and is therefore critical for male fertility.

Dynamics of microtubules

Filamentous polymers called microtubules play vital roles in chromosome segregation and molecular transport. An LMU team has now examined how microtubule lengths vary in response to changes in the availability of their protein ...

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