Sequencing the genomes of a microbial ecosystem

Corn stalks rustle and tractors trundle along, their wheels grinding into the Kansas soil. While it seems like farmers and machinery conduct most of the work on a modern farm, much of the heavy lifting goes on below the surface. ...

International competition benchmarks metagenomics software

Communities of bacteria live everywhere: inside our bodies, on our bodies and all around us. The human gut alone contains hundreds of species of bacteria that help digest food and provide nutrients, but can also make us sick. ...

Uncovering hidden microbial lineages from hot springs

Although global microbial populations are orders of magnitude larger than nearly any other population in, on or around the planet, only a fraction has been identified thus far. The U.S. Department of Energy (DOE) is seeking ...

Better microbial genome binning with metaBAT

DOE JGI researchers have developed an automated tool called MetaBAT that automatically groups large genomic fragments assembled from metagenome sequences to reconstruct single microbial genomes.

A history of phage-host interactions with help from CRISPRs

Using metagenomic datasets produced from the Iron Mountain site in Northern California and customized tools, researchers used bacterial spacer sequences commonly called CRISPRs to link phage and hosts in ecological studies.

Automating microbial genome sequence decontamination

Single cell genomics and metagenomics are pioneering techniques that have helped researchers assess environmental microbial community structure and function. As projects applying these techniques scale up, however, researchers ...

A revolutionary approach to studying the intestinal microbiota

An international research team within the MetaHIT consortium coordinated by INRA and involving teams from CEA, CNRS and Université d'Evry, has developed a new method to analyse the global genome, or the metagenome of the ...

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